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Dr. Michael Fuson
| Affiliation: | Faculty |
| Title: | Associate Professor |
| Office: | 108 Ebaugh |
| Email: |
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| Phone: |
740-587-6782
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B.A. from Haverford College, 1976
M.S. from Yale University, 1979
Ph.D. from Yale University, 1982
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Field of Interest:
I am interested in internal motion in macromolecules, ranging from synthetic polymers to lipids and peptides. This interest began with my doctoral studies which used NMR spin relaxation to study molecular motion in model biomembranes. Such motions are involved in many of the functional properties of the membranes, such as permeation of small molecules and the interactions of the different membrane components. During my post-doctoral work I began studying the local motions of synthetic polymers in solution. Local motions in polymers are as fast as the motions of small molecules, which is interesting given the huge size of polymer molecules. My own work has focused on characterizing the anisotropy of that motion, with the hope of shedding light on the 3-D details of the motion. I spent the 1995-1996 school year at the University of Wisconsin, Madison, where I became involved in doing computer simulations of the same dynamic processes I had been studying experimentally. Most recently, I have been using both spin relaxation and molecular dynamics simulation to study the internal motion of a small unstructured peptide, leucine enkephalin. It has been exciting to see how experimental and theoretical tools can complement each other in helping to understand molecular motions.
Teaching
Chem 121 - General Chemistry I plus laboratory
Chem 122 - General Chemistry I plus laboratory
Chem 341 - Thermodynamics and Kinetics plus laboratory
Chem 342 - Quantum Chemistry and Spectroscopy plus laboratory
Honors 196 - Scientists' Ways of Knowing (a seminar on the history and philosophy of science)
ex. GEOL 200 - Senior Research, Honors Projects, and Summer Research Interns:. Anna Belu '90, Ed Oliver '92, Jason Miller '92, Laura Lowe (Oberlin '93), Nelson Sefara '93, Benita Sizemore '93, Tracy Peterson '94, Brian Klei '94, Kent Hanser '94, Jason Wolford '95, Sachin Silva '95, Joel McFarland '98, Melicia Cottrill '99, Wendy Collins '99, Pete Scully '00, Jason Gulish '02, Brant Eutzy'03, Emily Trunkley '04, Ryan Gingo '08, Russ Bornschein '09, Christopher Bennett '10, Colin Murphy'10
Publications
M. M. FUSON and J. E. McFarland*. Concentration Dependence of Dipole-Dipole Cross-Correlation Spectral Densities in Polymer Solutions. Journal of Magnetic Resonance.
J. L. Fantini, M. M. FUSON, and T. A. Evans. 2006. Popping Popcorn Kernels: Expanding Relevance with Linear Thinking. Journal of Chemical Education. v. 83 p. 414-416
M. M. FUSON and M. D. Ediger. 1997. Dynamics of Poly(ethylene oxide) in Solution: 1. Localization of Chain Motion. Macromolecules. v. 30 p. 5704-5713
M. M. FUSON, K. H. Hanser* and M. D. Ediger. 1997. Local Dynamics of Poly(ethylene oxide) in Solution: 2. Vector Autocorrelation Functions and Motional Anisotropy. Macromolecules. v. 30 p. 5714-5720
M. M. FUSON and B. R. Klei*. 1996. Anisotropy of Local Dynamics of Polyethylene. v. 29 p. 5223-5227
M. M. FUSON. Coupled Spin Relaxation in Polymers. Encyclopedia of Nuclear Magnetic Resonance, D. M. Grant and R. K. Harris, ed., (John Wiley & Sons: Chichester, 1996) . v. 4 p. 1466-1472
(* signifies undergraduate co-author)
Presentations
M. M. FUSON . 2008. Comparison of Spin Relaxation and Molecular Dynamics Simulation Studies of the Dynamics of Leu5-Enkephalin. 49rd Experimental NMR Conference. Asilomar, CA
M. M. FUSON. 2004. Anisotropic Motion in Leu-Enkephalin Studied Using Cross-Correlation Effects in Spin Relaxation. 45rd Experimental NMR Conference. Asilomar, CA
M. M. FUSON. 2003. Dynamics Of Rubberlike Polymers In Solution Studied By Coupled Spin Relaxation And Molecular Dynamics Simulations. 44rd Experimental NMR Conference. Savannah, GA
M. M. FUSON . 2002. Leu-Enkephalin Dynamics as Studied Using Coupled Spin Relaxation. 43rd Experimental NMR Conference. Asilomar, CA
M. M. FUSON. 2001. Dynamics of Isobutylene in Solution Studied by Coupled Spin Relaxation. 42nd Experimental NMR Conference. Orlando, FL
M. M. FUSON. 1999. Coupled Spin Relaxation Studies of Polymers in Solution. 31st ACS Central Regional Meeting. Columbus, OH
Recent Student Presentations
Ryan Gingo* and M. M. Fuson. 2006. An Investigation of the Motions of Enkephalins Using NMR Spin Relaxation. 232nd American Chemical Society National Meeting & Exposition . San Francisco CA
Emily F. Trunkely* and M. M. Fuson. 2004. NMR Spin Relaxation Studies of the Motional Dynamics of Leu-Enkephalin. 227th American Chemical Society National Meeting. San Francisco CA
(* signifies undergraduate co-author)
