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Office of Security, Safety and Risk Management

Chemical Hygiene Plan


D. PROCEDURES FOR CARCINOGENS, REPRODUCTIVE TOXINS, SUBSTANCES THAT HAVE A HIGH DEGREE OF ACUTE TOXICITY, AND CHEMICALS OF UNKNOWN TOXICITY
Follow the procedures described in this section when performing laboratory work with greater than 10 mg of any carcinogen, reproductive toxin, substance that has a high degree of acute toxicity, or a chemical whose toxic properties are unknown.
1. The following definitions will apply:
a. Select carcinogen: Any substance defined as such in 29 CFR 1910.1450 and any other substance described as such in the applicable MSDS.
b. Reproductive toxin: Any substance described as such in the applicable MSDS, or any substance identified as a reproductive toxin by the Oak Ridge Toxicology Information Resource Center (TIRC), (615) 576-1746, or, for teratogens only, any substance identified as such in Thomas H. Shepard, "Catalog of Teratogenic Agents", 6th Ed., Johns Hopkins Press, 1989.
c. Substances with a high degree of acute toxicity: Any substance for which the LD50 data described in the applicable MSDS, cause the substance to be classified as a "highly toxic chemical" as defined in ANSI Z129.1.
d. Chemical whose toxic properties are unknown: A chemical for which there is no known statistically significant study conducted in accordance with established scientific principles that establishes its toxicity.
e. For the purpose of this CHP, chemicals in these four categories will be called "inimical".
f. Designated area: A hood, glove box, portion of a laboratory, or an entire laboratory room designated as the only area where work with quantities of the inimical chemicals in excess of the specific limit shall be conducted.
2. Designated areas shall be posted and their boundaries clearly marked. Only those persons trained to work with inimical chemicals will work with those chemicals in a designated area. All such persons will:
a. Use the smallest amount of chemical that is consistent with the requirements of the work to be done.
b. Use high efficiency particulate air (HEPA) filters or high efficiency scrubber systems to protect vacuum lines and pumps.
c. Store inimical chemicals or remove them from storage.
d. Decontaminate a designated area when work is completed.
e. Prepare wastes from work with inimical chemicals for waste disposal in accordance with specific disposal procedures consistent with the Resource Conservation and Recovery Act (RCRA) and as designted by Denison University's hazardous waste officer.
3. Store all inimical chemicals in locked and enclosed spaces with a slight negative pressure compared to the rest of the building, if such space is available.
4. Because the decontamination of jewelry may be difficult or impossible, do not wear jewelry when working in designated areas.
5. Wear long-sleeved disposable clothing and gloves known to resist permeation by the chemicals to be used when working in designated areas.